| Rank | City | Date | Scale | Fatalities | Injuries |
| 1 | Woodward | 4/9/1947 | F5 | 116 | 782 |
| 2 | Snyder | 5/10/1905 | F5 | 97* | 58* |
| 3 | Peggs | 5/2/1920 | F4 | 71 | 100 |
| 4 | Antlers | 4/12/1945 | F5 | 69 | 353 |
| 5 | Pryor | 4/27/1942 | F4 | 52 | 350 |
| 6 | (Bridge Creek-Newcastle-Moore-Oklahoma City) | 5/3/1999 | F5 | 36 | 583 |
| 7 | Oklahoma City | 6/12/1942 | F4 | 35 | 100 |
| 8 | Cleveland County | 04/25/1893 | F4 | 33 | ~100 |
| 9 | (Newcastle-South Oklahoma City-Moore) | 5/20/2013 | EF5 | 24 | – |
| 10 | Bethany | 11/19/1930 | F4 | 23 | 150 |
Source: National Weather Service Weather Forecast Office, Norman, OK
