First Known LSD Experience in History

It was in 1943 when Swiss scientist Albert Hofmann (credited with the synthesis and discovery of  LSD-25) inadvertently ingested lysergic-acid-diethylamide, (easy to do since it only takes an infinitesimal amount to become activated in the human mind) , from leftover ergot fungus, which grows in rye kernels.

This left over fungus, as recounted by Hoffmann, had been setting on a shelf in a jar for five years after having been tested in animals only. Below is an account of the 1943 synthesis experience with the left over fungus in Dr. Hofmann’s own words:

” In the final step of the synthesis, during the purification and crystallization of lysergic acid diethylamide in the form of a tartrate (tartaric acid salt), I was interrupted in my work by unusual sensations. The following description of this incident comes from the report that I sent at the time to Professor Stoll: Last Friday, April 16,1943, I was forced to interrupt my work in the laboratory in the middle of the afternoon and proceed home, being affected by a remarkable restlessness, combined with a slight dizziness. At home I lay down and sank into a not unpleasant intoxicated-like condition, characterized by an extremely stimulated imagination. In a dreamlike state, with eyes closed (I found the daylight to be unpleasantly glaring), I perceived an uninterrupted stream of fantastic pictures, extraordinary shapes with intense, kaleidoscopic play of colors. After some two hours this condition faded away. ” Source LSD My Problem Child by Albert Hofmann

Source: Michael Pollan How to Change Your Mind CSPAN July 4, 2018